Fractal Genomics
From ResearchID.org
Fractal Genomics is the fractal analysis of DNA for higher order semantic structures, especially in the genome's non-coding region.
Darwinists (1978) referred to non-coding DNA as "Junk DNA", containing but "fossil genes." [1] By contrast, Werner Gitt described a five level information hierarchy, expecting major levels of information beyond DNA statistics and gene identification. Jonathan West (1998), William Dembski (1998) and other Intelligent Design practioners predicted major useful functions would be found in the non-coding DNA.[2], [3] The explosion of genomic data is leading to research seeking higher levels of DNA information including syntax, semantics, genomic language and higher level pragmatics. An International PostGenetics Society has been established focusing on such analysis.[4]
Researchers have begun to discover fractal properties in DNA, DNA patterns or pyknons, and the existance of a nucleosome code. Recent research has begun to reveal fractal properties in DNA. These promise to further full the ID prediction of major functions in "non-coding DNA."
- A. Pellionisz (2002) filed a patent for the FractoGene software for fractal analysis of self-similar genomic repetitions.[5]
- Rothemun et al. (2004) report on DNA Sierpinski triangles suggesting the potential for fractal analysis of DNA.[6]
- Benoit Mandelbrot (2004) encouraged fractal analysis of DNA. [7]
- Simons & Pellionisz (2006) found triangulation of self-similar DNA components in Purkinje cell development. [8] They: "expect that a new generation of data mining tools will be required to support recursive fractal geometrical, combinatorial, and neural network models of the genomic basis of morphogenesis."
- Pellionisz (2006) discovered fractal properties in pyknons
References
- ↑ Susumu Ohno, So Much 'Junk DNA' in our Genome Brookhaven Symposium on Biology in 1972
- ↑ Pa. Trial Will Ask Whether 'Alternatives' Can Pass as Science, Rick Weiss and David Brown, Washington Post, Monday, September 26, 2005; Page A08
- ↑ Science and Design, William A. Dembski, First Things, October 1, 1998
- ↑ Pellionisz, A. Postgenetics: Genetics beyond Genes. The Journey of Discovery of the Function of "Junk DNA" 15 May, 2006, IPGS European Inaugural conference.
- ↑ Pellionisz, A. (2002) FractoGene: Utility to use self-similar repetitions in the language-like genetic information as fractal sets. US Patent Application (Aug. 1st, 2002)
- ↑ Rothemund PWK, Papadakis N, Winfree E [2004] 'Algorithmic self-assembly of DNA Sierpinski triangles': PLoS Biol 2(12): e424 - 7 December 2004
- ↑ Benoit Mandelbrot Keynote Lecture, Bioinformatics Conference, IEEE, ECSB2004, Stanford, August 18, 2004
- ↑ Simons, M, Pellionisz, A; Genomics, morphogenesis and biophysics: Triangulation of Purkinje cell development, The Cerebellum; 2006; 5(1): 27-35
