Irreducible complexity in biology

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Irreducible Complexity is a characteristic of systems "wherein the removal of any one of the parts causes the system to effectively cease functioning."[1] This IC List is a collection of components and systems that have been proposed as irreducibly complex and who they were originally proposed by.

Contents

Micro Components

See Molecular machines

Bacterial flagellum

Bacteria flagellum --- source url & source page
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Bacteria flagellum --- source url & source page

Proposed: Michael Behe[3]

Protein folding

Chaperonin --- source url & source page
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Chaperonin --- source url & source page

Proposed: Jerry Bergman[4]

Cilia

Cilia --- source url & source page

Molecular Cell Biology

Proposed: Michael Behe[5]

ATP synthase

ATP synthase --- [ source url] & source page
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ATP synthase --- [ source url] & source page

Proposed: Jerry Bergman in ATP: The Perfect Energy Currency for the Cell[7]

DNA - ribosome system

Ribosome --- source url & source page
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Ribosome --- source url & source page

Transcription regulation

Proposed by: Michael Behe[8]

The IDEA Center elaborates: The DNA - Enzyme System is Irreducibly Complex

Protein transport

Kinesin --- source page
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Kinesin --- source page

Proposed by: Michael Behe[9]

DNA supercoils

Proteins (green), DNA bases (blue), DNA backbone (red). --- source page
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Proteins (green), DNA bases (blue), DNA backbone (red). --- source page

Proposed by: Michael Behe[10]

Electron transport

Bacterial photoreaction center, an electron transport enzyme --- source url & source page
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Bacterial photoreaction center, an electron transport enzyme --- source url & source page

Proposed by: Michael Behe[11]

Telomeres

Cdc13-DNA complex --- source url & source page
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Cdc13-DNA complex --- source url & source page

Proposed by: Michael Behe[12]

Photosynthesis

Chlorophyll --- source url & source page
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Chlorophyll --- source url & source page

Proposed by: Michael Behe[13]

Blood Clotting

A blood clot complex --- source url & source page
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A blood clot complex --- source url & source page

Proposed: Michael Behe[14]

Candidates

Structures and systems that are being evaluated to determine if they are irreducibly complex.

Macro Systems

Simplest self reproducing cell

The simplest self reproducing cell is considered irreducibly complex and not amenable to abiogenesis.

Meso Systems

Eye

Complex Body Systems

Howard Glicksman, MD (Dr. G) in Exercise your Wonder reviews numerous systems of complex body parts.[15] He challenges proponents of evolution to show how these could be developed by small incremental changes when lack or poorly functioning components cause death.

Carnivorous Plants

Carnivorous Plants Wolf-Ekkehard Lo¨nnig and Heinz-Albert Becker, (Max-Planck-Institute for Plant Breeding Research, Cologne, Germany) cite:

Utricularia ‘is a complex bit of mechanism and offers, as yet, an intractable problem in evolution’
Juniper BE, Robins RJ and JoelDM(1989) Carnivorous Plants. London: Academic Press, p 117
‘the evolution of leaves with trap systems from noncarnivorous ones is mysterious, and there are no widely accepted hypotheses’
Rivadavia F, Kondo K, KatoMand HasebeM(2003) Phylogeny of the sundews, Drosera (Droseraceae), based on chloroplast rbcL and nuclear 18S ribosomal DNA sequences. American Journal of Botany 90: 123–130. Lo¨nnig and Becker further observe that:
Some biologists believe that the trap mechanism(s) of Utricularia and several other carnivorous plant genera (Dionaea, Aldovanda, Genlisea) come at least very near to ‘such a case’ of irreducible complexity.

Contingency Designs

Redundancy

Robustness

Regeneration

Heart Regeneration

Tail Regeneration

See tail regeneration in the salamander, lizard, newt etc.

Axoneme

Axoneme --- source url & source page
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Axoneme --- source url & source page

Haixan Sui & Kenneth H. Downing provide detailed structure of the axoneme microtubule doublets.[16], [17]

Proposed: (need cite)

Tubulin

Tubulin --- source url & source page
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Tubulin --- source url & source page

Mystery of Vital Cell Protein Solved After 30 Years

Proposed: (need cite)

Error Correction

The Elimination of Mutations by the Cell’s Elaborate Protein Quality Control Factory: A Major Problem for Neo-Darwinism Creation Research Quarterly Vol. 43, (2006-2007) #2

Systems having distinct IC cores

Eukaryotic RNA PolII

Weaver RF (2005) Molecular Biology (3rd ed.), p. 278.

References and notes

  1. Darwin's Black Box: The Biochemical Challenge to Evolution, Michael J. Behe, 1996, ISBN 0684834936.
  2. Molecular Machines: Experimental Support for the Design Inference, C.S. Lewis Society, Cambridge University, Summer 1994 meeting. See also Michael J. Behe, Molecular Machines: Experimental Support for the Design Inference, Cosmic Pursuit, March 1, 1998
  3. responded to critics & Michael Behe, A response to critics of Darwin's Black Box, ISCID
  4. http://www.creationresearch.org/creation_matters/pdf/2001/cm0606.pdf
  5. Darwin's Black Box: The Biochemical Challenge to Evolution, Michael J. Behe, 1996, ISBN 0684834936.
  6. Cornelius Hunter, ATP Synthase: Paley's Secret Spring, IDtheFuture Sept. 12, 2006
  7. ATP: The Perfect Energy Currency for the Cell Jerry Bergman, ATP: The Perfect Energy Currency for the Cell, Creation Research Society Quarterly, Vol. 36, No. 1 (1999)
  8. Molecular Machines: Experimental Support for the Design Inference, Cosmic Pursuit, March 1, 1998
  9. Molecular Machines: Experimental Support for the Design Inference, Cosmic Pursuit, March 1, 1998
  10. Molecular Machines: Experimental Support for the Design Inference, Cosmic Pursuit, March 1, 1998
  11. Molecular Machines: Experimental Support for the Design Inference, Cosmic Pursuit, March 1, 1998
  12. Molecular Machines: Experimental Support for the Design Inference, Cosmic Pursuit, March 1, 1998
  13. Molecular Machines: Experimental Support for the Design Inference, Cosmic Pursuit, March 1, 1998
  14. Darwin's Black Box: The Biochemical Challenge to Evolution, Michael J. Behe, 1996, ISBN 0684834936.
  15. Howard Glicksman, Exercise Your Wonder, ARN.org
  16. Haixan Sui & Kenneth H. Downing, Secrets of a Cellular Machine: New Clues to the Architecture of Flagella and Cilia] Julyl 26, 2006 Lawrence Berkeley Lab.
  17. Haixan Sui & Kenneth H. Downing, Molecular architecture of axonemal microtubule doublets revealed by cryo-electron tomography] Nature Letters 2006 doi:10.1038/nature04816

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